Olga ran

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How is Ran involved in nuclear transport? Cargo is transported through pores in the nuclear envelope, in association with carriers that bind to pore proteins called nucleoporins. A Ran–GTP gradient across the envelope is created by the asymmetric distribution of the GTPase activating protein known as RanGAP, which is in the cytosol, and of the guanine nucleotide exchange factor RanGEF in the nu...

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In Memoriam: Olga Taussky-Todd

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Small GTPase Ran and Ran-binding proteins.

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2015

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.140600